Mice expressing cre ubiquitously were generated by microinjecting linearized plasmid pBS185 DNA containing the cre recombinase gene under control of the human cytomegalovirus promoter into male pronuclei of (CBA x C57BL/6)F1 embryos. Several founders were generated, with two showing a high gene/locus deletion rate when crossed to floxed animals. (J:118712)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(CBA x C57BL/6)F1
--
Insertion
--
--
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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