A targeting vector was designed to insert a lacZ-neo cassette in frame into the second exon immediately downstream of the initiation ATG. Western blot failed to detect protein in mutant kidney samples, and lacZ expression was detected by X-gal staining. (J:119488)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count