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Targeting vectors containing loxP sites in the DiGeorge syndrome critical region gene 2 and armadillo repeat gene deleted in velo-cardio-facial syndrome were introduced into ES cells in trans. Subsequent transient cre expression in ES cells containing loxP sites on opposite chromosomes resulted in the reciprocal duplication of the Dcgr2-Arvcf interval. (J:64380)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
