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The mouse Lta gene was fused with the transmembrane domain of Ltb and inserted into a vector containing the mouse Ig kappa (Igk) promoter and enhancer elements. Mice generated have multiple copies of the transgene and express a membrane form of lymphotoxin alpha (LTa) under control of the kappa light chain enhancer and promoter. The LTa transgene is selectively expressed in B lymphocytes. (J:73100)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
