This allele contains a single loxP site in place of DQ52, following cre mediated deletion of a floxed neomycin resistance cassette and HSV-tk that had been inserted in place of DQ52 and all its flanking sequences. In addition, the targeting vector replaced a wild-type HindIII site between JH3 and JH4 with an EcoRV site. (J:119484)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count