2kb of the human promoter and 3kb of downstream sequence were used to drive the expression of Cre in the brain and spinal cord. Two lines were created (lines 50 and 13) with only line 50 exhibiting expression. Crosses to a LacZ reporter strain was used to test the transgene insertion where by recombination resulted in neural LacZ expression. (J:77229)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
--
Insertion
--
--
--
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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