A neo cassette was inserted into exon 3 resulting in a null allele. Targeted mutation was confirmed by northern and western blot that showed no RNA or protein expression, respectively, in spleen tissue. (J:119326)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count