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EN
The Cre recombinase coding sequence, modified by addition of a Kozak consensus translation start sequence and nuclear localization signals, was inserted into the p1017 expression vector between the thymocyte-specific, mouse proximal Lck promoter and most of the human growth hormone gene, extending from within exon 1 through the polyadenylation signal. Cre recombinase activity is restricted to thymocytes; evidence of activity in spleen is attributed to the presence of thymus-derived T lymphocytes. (J:67674, J:81268)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
