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A retroviral vector was inserted into the third intron and contained a splice acceptor, termination codons in all reading frames, a selection marker and a transcription terminator. This design would interrupt the transcript before exon 4, which contains TM7 of the 7-transmembrane domain and the C-terminal domain. RT-PCR confirmed absence of wild-type transcript in mutants. (J:117649)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
