Exon 5 was floxed by the insertion of a floxed neo cassette and an additional loxP site 3' of exon 5. Subsequent removal of the floxed neo cassette from ES cells was achieved by transient cre expression. (J:118802)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count