The Cre-ERT2 expression cassette was placed under the regulatory control of the mouse cadherin 5 promoter. 8 lines were obtained. Line CIVE23 inserted 138 kb upstream of Ankrd50 (chr3:38,522,028; NCBI37/mm9) with a fragment of Vat1l and a 87.6 kb genomic duplication occured at the integration site. (J:116638, J:240920)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count