A 5.5 kb enhancer element, located 3' to the Wnt1 polyadenylation signal sequence, was replaced with a floxed PGKneo selection cassette by homologous recombination. This cassette was removed by cre recombination via injection of a cre-encoding plasmid into pronuclei of zygotes from heterozygous intercrosses. (J:118582)
Basic Information
129S1/Sv-Oca2+ Tyr+ Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count