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A targeting vector was used to place a floxed neomycin-thymidine kinase expression cassette upstream of exon two and an additional loxP site in intron 2. ES cells were transfected with Cre expression plasmid to excise the neo fragment, leaving the floxed gene. (J:79167)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
