A targeting vector was used to place a floxed neomycin-thymidine kinase expression cassette downstream of the single coding exon, and a loxP site upstream. Transient Cre expression in targeted ES cells excised the neo cassette and left the floxed exon. (J:132967, J:149909)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count