Crossing Casktm1Sud mutants with cre-expressing mice results in excision of the floxed exon and neomycin cassette creating a null allele. Cask expression is decreased ~33% in heterozygotes and is abolished in homozygotes. (J:117978)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count