The coding region of mouse PON1 was placed under the control of the macrophage-specific human scavenger receptor A (MSR1) gene regulatory elements and the human growth hormone polyadenylation signal. Analysis of mRNA from transgenic mice showed that the construct was expressed only in circulating monocyte/macrophages and tissues containing resident macrophages (i.e., liver, lung, spleen, but not in heart, kidney, brain, or skeletal muscle). (J:118732)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6J
--
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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