Threonine codons 76 (ACC) and 86 (ACT) were changed to alanine (GCC, GCT) (p.T76A, p.T86A). The loxP site flanked neomycin resistance gene cassette that was inserted into intron 6 was removed through subsequent Cre-mediated recombination. (J:118244)
Basic Information
129S4/SvJae-Tg(Prm-cre)70Og
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count