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The entire coding region was deleted and replaced with beta-galactosidase and neomycin resistance genes. The mutation removes all eight zinc finger domains from the gene and results in the fusion of 39 amino acids at the N terminal of Sall4 and beta-galactosidase. Although a beta-galactosidase gene was inserted, lacZ is not expressed. (J:118119)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
