A targeting vector was designed to insert a cDNA encoding the human diphtheria toxin receptor (HBEGF/DTR) fused to sequences encoding a green fluorescent protein (GFP) equipped with an internal ribosome entery (IRES), IRES-DTR-GFP with a floxed neo into the 3' untranslated region downstream of exon 11 of the Foxp3 gene. (J:117743)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count