A targeting vector was designed to insert a TM-lacZ gene and a neomycin selection gene into the locus, replacing the coding sequence spanning from exon 2 to exon 5. The first 32 amino acids fused to the TM-lacZ after splicing. Staining confirmed expression of lacZ under the control of the endogenous promoter. (J:117678)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129S6/SvEvTac x C57BL/6NTac)F1
Targeted
Insertion, Intragenic deletion
--
1
--
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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