A transgenic construct was generated in which the codon optimized reverse tetracycline transactivator (rtTA) was placed under control of a skeletal muscle-specific version of the mouse muscle creatine kinase (Ckm) promoter. RT-PCR analysis showed that transgenic mice containing this construct expressed rtTA almost exclusively in skeletal muscles. (J:118351)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count