The mouse amelogenin promoter was used to drive expression of dentin phosphoprotein ectopically in the enamel organ. Mice derived from line 13 are representative of lines 10, 46, and 53. all of which carry a single copy of the inserted transgene construct. Line 47 carries more than 10 and probably around 23 copies of the insert and displays a diverging phenotype. (J:101218)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6J x DBA/2J)F1 x CBA/J
--
Insertion
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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