The transgene consists of a cDNA encoding soluble mouse Crry under the control of the mouse MT-I promoter, the human growth hormone polyadenylation sequence, and the mouse MT gene 5' and 3' flanking regions, which serve as locus control regions to confer position-independent and copy number-dependent expression to the transgene. (J:117777)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count