A floxed neomycin resistance cassette was inserted in the intron between exons c2 and d. A third loxP was inserted in the intron between exons e and f. The floxed neo was subsequently removed from one correctly targeted ES cell clone using a cre expression vector. Resulting mice have loxP sites flanking exons d and e. (J:125373)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
BALB/c
Targeted
Insertion
--
1
3
25

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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