The pGT1Lxf gene trap vector, containing a splice-acceptor sequence upstream of a betageo, was inserted into exon 2. The resulting transcript contains exons 1 and 2 from the locus and the betageo. Nortern and Western blot analyses confirmed absence of wild type expression of paraoxonase 2 transcript and protein, respectively. (J:116935)
Basic Information
Insertion of gene trap vector
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count