The first coding exon of the Cask gene is flanked by loxP sites and a neomycin cassette is inserted into the intron adjacent to the floxed intron. The resulting allele is a hypermorph with Cask expression decreased by ~66%. (J:117978)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count