This transgene expresses a mouse Tnnt2 gene, with codon 92 mutated to encode a leucine instead of the arginine and an 11-amino acid c-myc epitope added to the 5' end of the coding region, under the control of a rat alpha-myosin heavy chain promoter. This line expresses 50% of the total Tnnt2 as the mutant transgenic form. (J:104369)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count