This transgene expresses a mouse Tnnt2 gene, with codon 92 mutated to encode an glutamine instead of the arginine and an 11-amino acid c-myc epitope added to the 5' end of the coding region, under the control of a rat alpha-myosin heavy chain promoter. This line expresses 92% of the total Tnnt2 as the mutant transgenic form. (J:56911)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
--
Insertion
--
1
--
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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