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EN
The targeting construct is designed to insert an internal ribosome entry site (IRES), a coding region for a nuclear-localized cre recombinase sequence, and an SV-40 poly(A) sequence, followed by an FRT-flanked neomycin resistance (neo) cassette, between the translational stop codon and transcriptional termination sequence within exon 19. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:115299)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
