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A cre-containing cassette including a nuclear localization signal and a polyadenylation sequence was inserted into the start codon of the LHRH gene by homologous recombination of the BAC, RP23-22J8 which includes 137 kb of 5' upstream and 73 kb downstream sequences around the LHRH coding sequence of the BAC. The modified BAC was then used to create transgenic mice. (J:115190)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
