This transgene consists of the mouse Plau gene under the control of the human scavenger receptor A promoter and enhancer, resulting in macrophage specific transgene expression. mRNA expression is increased 40-fold and activity is elevated as much as 500-fold in stimulated peritoneal macrophages. (J:102208)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6 x SJL
--
Insertion
--
1
--
10

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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