This transgene consists of the mouse Plau gene under the control of the human scavenger receptor A promoter and enhancer, resulting in macrophage specific transgene expression. mRNA expression is increased 40-fold and activity is elevated as much as 500-fold in stimulated peritoneal macrophages. (J:102208)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count