Produced by targeted meiotic recombination in a cross between engineered loxP sites in the presence of Tg(Sycp1-cre)4Min. The entire the Hoxd1 through Hoxd10 genes are deleted. Hoxd11, Hoxd12 and Hoxd13 are brought into the vicinity of a possible early limb control region. (J:91567)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S2/SvPas
Targeted
Intergenic deletion, Intragenic deletion
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6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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