The rearranged 3-83 heavy chain was inserted into the IgHa locus via homologous recombination. A floxed neo selection cassette was also introduced and subsequently removed by Cre mediated recombination. (J:111431)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count