Log In|Sign Up
EN
This allele is a derivative of Apctm2Rak in which the loxP-flanked exon 14 sequences have been deleted by Cre-mediated recombination in the germline. A single loxP site remains in place of exon 14 and flanking intronic sequences. Loss of exon 14 is predicted to introduce a frameshift mutation and a premature stop codon, resulting in a truncated protein. (J:114152)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
