A full-length cDNA encoding human hepatocyte growth factor was inserted into an epidermis-directed expression cassette containing 2500 bp of 5' flanking plus untranslated-region DNA from the human keratin 14 gene, a rabbit beta-globin intron, and approximately 7 kb of 3' untranslated-region plus flanking sequence from the human keratin gene. Immunohistologic analysis demonstrates expression in the epidermis. (J:84399)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count