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A floxed neomycin resistance gene, as well as the 564 VkappaJkappa5 region from a hybridoma derived from an autoimmune SWRxNZB mouse, replaced a segment of DNA including the entire J kappa region. Male chimeric mice were bred to C57BL/6 females. Offspring from these mice were crossed with cre expressing transgenic mice in order to excise the neomycin resistance cassette. (J:113555)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
