Exon 2 was flanked by loxP sites. Exon 2 contains the first translated region of the gene. The vector contained an FRT-flanked neo cassette that was subsequently removed by crossing with FLPe deleter mice. (J:113256)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count