Deletion of exons 8 and 9, which encode the DNA-binding region, was accomplished by mating mice contining loxP sites in introns 7 and 9 to CMV-Cre mice. Resulting progeny carried a deletion of the sequences flanked by the loxP sites. (J:121823)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count