LoxP sites were inserted to flank exons 4 and 5. Exon 4 contains the ATG and exon 5 contains a portion of the protein critical for telomere binding. (J:112184)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count