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A novel type II early transposon (ETnIIbeta) spontaneously inserted 1.6 Kb downstream of the polyadenylation signal of Dusp9 between two repetitive sequences (SINE and LINE elements) at position ChrX: 73645160 (GRCm38/mm10). This insertion does not disrupt Dusp9, Pnck or any other gene or noncoding RNA. RT-PCR and western blot analysis confirmed increased Dusp9 transcript and protein expression, respectively, in mutant ES cells. (J:207896)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
