Exon 1 is flanked between a loxP site before the transcriptional initiation site and another loxP site within intron 1. A FRT-neo-FRT selection cassette was also inserted before the intronic loxP site. (J:111794)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count