Exon 1 was disrupted through insertion of an IRES-lacZ and neo cassette. In situ hybridization analysis confirmed the absence of mRNA in E6.5 homozygous embryos. (J:112167)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count