Two loxP sites were inserted flanking exons 7 and 8, which are upstream of the exons encoding the zinc fingers. A neo cassette flanked with FRT sites was also inserted upstream of exon 7 and then removed with flp DNA recombinase. (J:108507)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count