Two loxP sites were inserted into the 5' UTR and the first intron via homologous recombination. A neomycin resistance gene flanked by two frt sequences was also introduced into the intron and then removed by crossing with ACTB-Flp mice. (J:111701)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count