A Beta-geo gene trap vector, pGTOpfs, was inserted into intron 5 of the locus. The first 122 amino acids were fused to the Beta-galactosidase-neomycin protein, thereby eliminating the proline rich stretch. Western blots demonstrate expression of chimeric protein composed of the endogenous N-terminal polypeptide fused to Beta-geo. (J:111801)
Basic Information
Insertion of gene trap vector
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count