A targeting vector was designed to flank exons 6-8 of the locus. This sequence encompasses the active site and surrounding parts of the catalytic domain. A floxed neo was removed via cre mediated excision. (J:111969)
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A targeting vector was designed to flank exons 6-8 of the locus. This sequence encompasses the active site and surrounding parts of the catalytic domain. A floxed neo was removed via cre mediated excision. (J:111969)