A targeting vector was designed to replace all of exon 3 and one third of exon 4, encoding the IgV and IgC domains, respectively, with a neomycin resistance gene. Absence of transcript was confirmed in mutant macrophages and B cells. (J:112130)
Basic Information
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count