Fas cDNA with a single nucleotide change leading to a I246N change in protein sequence, which codes for Fascg was subcloned into the rat insulin 2 promoter and injected into NOD/Lt oocytes to produce transgenic mice. (J:81416)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
NOD/ShiLt
--
Insertion
Dominant
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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