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An NLS-lacZ gene followed by a self-excising protamine-cre neomycin selection cassette was fused in-frame to the initiation codon of the gene. Following passage through the male germline of the founder chimeric mouse, the neomycin selection cassette was deleted, leaving the lacZ gene and a single loxP site in place. Beta-galactosidase is expressed from this allele under the control of the endogenous promoter. (J:112173)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
