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A neomycin selection cassette was inserted into exon 6. Northern blot and RT-PCR analysis indicated that aberrant in-frame splice transcripts lacking exon 6, exons 5 and 6 or exons 6 and 7 are expressed from this allele. Mutant proteins with partial function are predicted to be expressed suggesting that this allele is a hypomorph. (J:112169)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
